Banca de DEFESA: FABIO AUGUSTO SILVA VIEIRA

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : FABIO AUGUSTO SILVA VIEIRA
DATE: 28/07/2025
TIME: 14:00
LOCAL: Plataforma Teams
TITLE:

SARCOPENIA AND SLEEP QUALITY IN PATIENTS UNDERGOING HEMODIALYSIS: SECONDARY ANALYSIS OF THE SARC-HD STUDY

KEY WORDS:

sarcopenia; sleep quality; hemodialysis; chronic kidney disease; muscle function

PAGES: 100
BIG AREA: Ciências da Saúde
AREA: Fisioterapia e Terapia Ocupacional
SUMMARY:

Introduction: Sarcopenia and sleep disorders are highly prevalent among patients with chronic kidney disease (CKD) undergoing hemodialysis (HD), negatively impacting clinical outcomes. Evidence from other populations suggests that poor sleep quality may contribute to the loss of muscle mass and strength; however, this relationship remains underexplored in the HD population. Materials and Methods: This observational, cross-sectional, and multicenter study analyzed data from HD patients recruited from five centers in the Federal District, Brazil. Sarcopenia was assessed according to the adapted criteria from the European Working Group on Sarcopenia in Older People 2 (EWGSOP2), through handgrip strength, gait speed, and calf circumference. Patients were categorized into two groups for analysis: without sarcopenia and with sarcopenia (including probable, confirmed, and severe stages). Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI) and ActTrust®-AT0503 actigraphy (Condor Instruments©). Poor sleep quality according to the PSQI was defined as a score ≥ 5. Statistical analysis included correlations and group comparisons based on sarcopenia status. Results: A total of 230 patients were analyzed (37% women, 48.5% older adults, and 31.9% undergoing hemodiafiltration). The prevalence of sarcopenia was 29.6%. Patients with sarcopenia had longer total sleep time (370 minutes vs. 308 minutes; p < 0.05). A lower proportion of patients with sarcopenia reported sleeping less than 6 hours (42% vs. 82%; p = 0.021). There was a negative correlation between PSQI scores and muscle strength (r = −0.18; p = 0.005) and a positive correlation with gait time (r = 0.15; p = 0.030). No significant correlation was found between calf circumference and sleep quality. Conclusion: Physical function, a key parameter of sarcopenia, was associated with sleep quality in CKD patients undergoing HD. Importantly, patients with sarcopenia exhibited longer total sleep time, indicating a possible link between these conditions. These findings underscore the importance of incorporating sleep assessment into the clinical management of this population, with a focus on interventions that promote muscular and functional health.

COMMITTEE MEMBERS:
Externo à Instituição - MAYCON DE MOURA REBOREDO - UFJF
Externo ao Programa - ***.072.301-** - EINSTEIN FRANCISCO DE CAMARGOS - UnB
Presidente - ***.419.421-** - HEITOR SIQUEIRA RIBEIRO - UnB
Interno - 2376346 - OTAVIO DE TOLEDO NOBREGA