Banca de QUALIFICAÇÃO: JULIANA ELVIRA HERDY GUERRA AVILA

Uma banca de QUALIFICAÇÃO de DOUTORADO foi cadastrada pelo programa.
STUDENT : JULIANA ELVIRA HERDY GUERRA AVILA
DATE: 22/09/2025
TIME: 09:00
LOCAL: A definir
TITLE:

“PESSOAS VÍTIMAS DE QUEIMADURAS: ASPECTOS EPIDEMIOLÓGICOS, LESÕES DE VIAS AÉREAS, LESÕES POR INALAÇÃO E DESFECHOS EM UM CENTRO DE REFERÊNCIA REGIONAL PARA TRATAMENTO DE QUEIMADOS”

KEY WORDS:

“ smoke Inhalation Injury, burns/mortality, incidence”

PAGES: 100
BIG AREA: Ciências da Saúde
AREA: Medicina
SUMMARY:

Introduction: “Burns are severe traumatic injuries associated with high morbidity and mortality. Inhalation injury, when present, worsens prognosis and significantly increases mortality, being considered a marker of severity. Objective: To evaluate the incidence and impact of inhalation injuries in burn victims, identifying factors associated with mechanical ventilation and hospital mortality in a Brazilian referral center. Methods: This retrospective and prospective cohort study included all patients admitted to the Burn Unit of the Hospital Regional da Asa Norte between January 2010 and December 2025. To date, data from patients hospitalized between January 2019 and December 2024 have been analyzed and are presented as partial results. Results: From January 2019 to December 2024, 1,486 patients were admitted, of whom 1,178 were aged ≥18 years. The mean age was 42.5 ± 15.1 years, and 32.5% were female. Inhalation injury was identified in 32 patients (2.7%). The mean total body surface area burned (TBSA) was 13.3 ± 15.6%, with 12.1% presenting TBSA >25%. Overall mortality was 4.2% (n = 49). Multivariate analysis showed that older age (OR = 1.029; 95% CI: 1.006–1.053; p = 0.014), ethanol as the combustion agent (OR = 2.869; 95% CI: 1.383–5.948; p = 0.005), and TBSA >25% (OR = 36.303; 95% CI: 17.040–77.344; p < 0.001) were independently associated with mortality. Among patients with inhalation injury (n = 32), most cases occurred in closed environments (84.4%), and 37.5% had TBSA >25%. In this subgroup, 25.0% required mechanical ventilation, 28.1% required vasoactive drugs, and hospital mortality reached 15.6%. Univariate analysis showed that the need for mechanical ventilation was associated with TBSA >25% (p < 0.001) and higher Baux Index (p = 0.007). Hospital mortality correlated with older age (p = 0.009), TBSA >25% (p = 0.002), dyspnea at admission (p = 0.049), and higher Baux Index (p = 0.010). Conclusion: These partial results suggest that although infrequent, inhalation injury is associated with greater clinical severity and higher hospital mortality. Advanced age, ethanol as the combustion agent, and TBSA >25% remain the main independent risk factors for death. Ongoing data collection will consolidate these findings and expand knowledge regarding the impact of inhalation injury in burn victims.”

COMMITTEE MEMBERS:
Externo à Instituição - BRUNO DO VALLE PINHEIRO - UFJF
Externo à Instituição - Dilson Palhares Ferreira - FEPECS
Presidente - ***.645.631-** - FABIO FERREIRA AMORIM - ESCS
Interno - ***.580.591-** - FRANCISCO DE ASSIS ROCHA NEVES - UNIFESP
Externo à Instituição - JORGE LUIS DOS SANTOS VALIATTI